Non-Invasive Prenatal Testing (NIPT)

Accurate, safe, and early screening for chromosomal anomaly from 10 completed weeks of pregnancy. At ROC, we offer Non-Invasive Prenatal Testing (NIPT) using the NIPT by TDL test (formerly known as the Harmony test). This advanced screening test is available from 10 completed weeks of pregnancy and provides an accurate assessment of your baby’s risk of having a chromosomal anomaly – without any risk to your pregnancy.

Non-Invasive Prenatal Testing (NIPT)

We offer 2 types of NIPT appointments:

  • NIPT screening only (blood test to determine chromosomal anomalies and sex chromosome disorders).

    The NIPT can also determine the sex of your baby. However, if you prefer not to know, simply let us know at your appointment.  

  • NIPT screening and early pregnancy ultrasound (scan) 

What is NIPT?

NIPT is a simple blood test that analyses small fragments of your baby’s DNA found in your blood during pregnancy. Unlike traditional prenatal screening methods, NIPT assesses the actual genetic material of the baby, offering higher accuracy for identifying certain conditions. 

What Conditions Does NIPT Screen For?

NIPT by TDL screens for the most common chromosomal anomalies: 

 

  1. Downs Syndrome (Trisomy 21) – Associated with intellectual disability, congenital heart defects, and other medical conditions. 

  2. Edwards Syndrome (Trisomy 18) – A serious condition often associated with miscarriage or severe birth defects. 

  3. Patau Syndrome (Trisomy 13) – Also linked to severe developmental abnormalities and a low survival rate beyond the first year. 

Chromosomes:

Sex chromosome conditions occur when there is a missing, extra, or incomplete copy of the X or Y chromosomes. The NIPT test with sex chromosome aneuploidy panel option can assess risk for XXX, XYY, XXY (Klinefelter syndrome), and a missing X chromosome in a girl (Turner syndrome).  

 

In addition, NIPT by TDL can detect: 

Sex Chromosome Aneuploidy:

Sex chromosome disorders, such as 

 

  • Turner syndrome (X or XO) 

 

  • Klinefelter syndrome (XXY) 

 

  • Triple X (XXX) 

 

  • XYY syndrome 

Please note, NIPT does not screen for non-chromosome disorders, familial mutations, malformations, fetal growth or fetal viability. 

Why Choose NIPT by TDL?

  • Available from 10 weeks of pregnancy 

 

  • High accuracy compared to traditional screening tests 

 

  • Safe and non-invasive – routine blood sample 

 

  • Fast results – typically returned within 4 working days 

 

  • Screens for both chromosomal conditions and sex chromosome anomalies 

How Does the NIPT Test Work?

  1. A blood sample is obtained from your arm, just like any routine blood test.

     

  2. The sample is analysed to identify your baby’s DNA and assess specific chromosomal conditions.

     

  3. Your NIPT results are combined with gestational age (weeks of pregnancy) to provide a clear risk estimate. You may already have attended your NHS early pregnancy scan appointment; therefore, we will require the date of your scan and gestational age calculated at your NHS appointment.

     

  4. If you are awaiting your NHS early pregnancy scan appointment and unsure of your dates, we provide ultrasound appointments at ROC Clinic from 6 weeks of pregnancy. For accuracy of NIPT results, should scan findings suggest you are less than 10 weeks, we will schedule your blood test (NIPT) accordingly (ie., appointment split into 2 visits).

     

  5. We will contact you promptly with your results and provide personalised support if further testing is recommended.  

What Happens After the Test?

If your NIPT result indicates a low risk, no further testing is recommended. If a higher risk is identified, we will discuss the available options, which include further diagnostic testing and arrange an urgent referral to a specialist team for support. 

Book Your NIPT Test Today

Our friendly and experienced team is here to support you through the stages of early pregnancy. If you’re over 10 weeks pregnant and would like to book a Non-Invasive Prenatal Test, contact us today to schedule your appointment or Book Online.